Ipamorelin (10mg)

A single-component research material supplied for controlled research environments. Suitable for studies exploring ghrelin (GHS-R1a) receptor–related pathways and assay development in model systems.

Composition

• Ipamorelin
• Appearance: Lyophilized powder in a sealed research vial

Research Focus (non-clinical)

• Peptide identity and purity assessment via HPLC/LC-MS
• Assay development and calibration for quantitative analysis of ghrelin-pathway models
• Chromatographic method optimization for impurity profiling and peak resolution
• Stability characterization of a lyophilized peptide under laboratory storage conditions

For qualified research professionals and institutional laboratories. Not for human use.

Documentation & Quality Assurance

Each lot is sourced through our verified global supply chain with emphasis on traceability and quality control. We work diligently to obtain and maintain third-party analytical reports (HPLC/LC-MS) and Certificates of Analysis for each batch, as part of our ongoing quality process. These documents are reviewed internally and displayed as they become available. Independent third-party testing is also performed on select lots to confirm identity, purity, and alignment with our internal specifications.

Important Notice

This product is intended for laboratory research use only. It is not intended for human or veterinary use, and must not be used for diagnostic, therapeutic, or clinical purposes.
This material is not a drug, medical device, or dietary supplement, and has not been evaluated by the U.S. Food and Drug Administration.

Quality & Manufacturing

All materials are sourced from carefully vetted domestic and international manufacturing partners who follow quality systems consistent with ISO and cGMP principles. Each supplier is reviewed for reliability, documentation integrity, and transparency in testing.

We require a verified purity of 99% or higher and perform independent third-party spot testing to confirm that select lots meet our internal standards for identity, purity, and composition. Where available, endotoxin testing results are included on Certificates of Analysis to verify laboratory purity; their inclusion is for research quality assessment only and does not imply suitability for human or veterinary use.

All research materials are sealed for integrity and packaged for stability during storage and transport from manufacturing through final delivery.

What It Is

Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH2) is a synthetic pentapeptide classified as a selective growth hormone secretagogue that acts at the growth hormone secretagogue (GHRP) receptor.

Research Background

Ipamorelin has been investigated in primary rat pituitary cell cultures (in vitro) and in vivo rodent and swine models, where its pharmacological selectivity profile was characterized against other growth hormone-releasing peptides (GHRPs) including GHRP-6 and GHRP-2. Chronic in vivo administration studies in young female Wistar rats examined its effects on somatotroph cell populations and pituitary responsiveness over 21-day treatment periods. Additional rodent studies have evaluated its activity in models of postoperative gastrointestinal dysmotility, and dose-response studies in adult female Sprague-Dawley rats assessed longitudinal bone growth rate and systemic growth factor parameters.

Observed Areas of Interest in Research

Research has focused on ipamorelin's agonism at the GH-secretagogue (GHRP) receptor, where in vitro studies in primary rat pituitary cells recorded an EC50 of approximately 1.3 nmol/l for growth hormone release, comparable to GHRP-6. A key area of inquiry has been receptor selectivity: unlike GHRP-6 and GHRP-2, ipamorelin did not stimulate ACTH or cortisol release in rat and swine models even at doses reported to exceed the ED50 for GH release by more than 200-fold, and FSH, LH, prolactin, and TSH plasma levels were not significantly altered in those studies. Researchers have also examined somatotroph granule density and intracellular GH content in pituitary cell cultures, as well as IGF-I and IGF-binding protein levels in bone-growth models, where dose-dependent increases in longitudinal bone growth rate were observed without corresponding changes in circulating IGF-I. Studies in rodent models have further explored ipamorelin's activity in the context of gastrointestinal motility, identifying effects on intestinal transit in a laparotomy-induced postoperative ileus model.

Research Notes

Purity verified by third-party laboratory analysis (Certificate of Analysis available on request). Supplied strictly for in-vitro and laboratory research use only. Not for human consumption.

All information above is provided for research and educational reference only and summarizes findings from published scientific literature (predominantly in-vitro and animal models). It does not describe outcomes in humans. This product is not a drug, dietary supplement, or article intended for human or veterinary use.

All products from Blitz Health are manufactured using a lyophilization (freeze-drying) process. This method is designed to maintain product integrity and allows vials to remain stable during shipping for approximately 3–4 months.

Once a vial is reconstituted with bacteriostatic water, it should be stored in the refrigerator to help maintain stability. Under these conditions, reconstituted material is generally considered stable for up to 30 days.

Lyophilization is a dehydration technique in which compounds are frozen and then exposed to low pressure. This causes the water in the vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure. This powder can be kept at room temperature until reconstitution.

Upon receipt, products should be stored away from heat and light. For short-term use, refrigeration at approximately 4°C (39°F) is suitable. For long-term storage (several months to years), vials may be placed in a freezer at approximately -80°C (-112°F). Freezing is the preferred method for preserving product stability over extended periods.

⚠️ Important Notice:
These products are intended for research use only. Not for human consumption.